Jasper van Bemmelen

ReSeT selects reference genomes by optimizing taxonomic discrimination and representativeness, improving profiling accuracy in high-ambiguity datasets.

This study benchmarks how reference genome selection affects taxonomic profiling accuracy across bacterial and viral datasets, showing context-dependent impacts on accuracy and computational efficiency.

AmpliDiff identifies discriminatory genomic regions and primers for accurate lineage abundance estimation in viral metagenomes, comparable to whole genome sequencing.