Author

Yu-Chen Cheng

Harvard UniversityORCID 0000-0003-1869-4760Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:trajectory inference· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Franziska Michor AiD· 2 shared Herbert LevineiD· 2 shared Shubham TripathiiD· 2 shared Thomas O. McDonaldiD· 2 shared Yun ZhangiD· 2 shared BV Harshavardhan· 1 shared Cristina GuarducciiD· 1 shared Daniel L. AbravaneliD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Franziska Michor AORCID

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2 papers

Recent·Most cited

BioinformaticsCell SystemsPeer-reviewedAug 1, 2026

PROFET Predicts Continuous Gene Expression Dynamics from scRNA-seq Data to Elucidate Heterogeneity of Cancer Treatment Responses

Yu-Chen Cheng, Hyemin Gu, Thomas O. McDonald…·Franziska Michor A

1 citation

𝕏 PostBluesky

Systems BiologybioRxivPreprintSep 19, 2023

Reconstruction of single cell lineage trajectories and identification of diversity in fates during the epithelial-to-mesenchymal transition

Yu-Chen Cheng, Yun Zhang, Shubham Tripathi…·Franziska Michor A

This study uses optimal transport analysis on scRNA-seq data to reconstruct EMT trajectories in MCF10A cells, identifying three distinct fates and novel genes associated with different EMT states.

3 citations

𝕏 PostBluesky