Fabian Brand

This paper introduces GestaltGAN, a generative model that creates photorealistic portraits of individuals with rare genetic disorders while preserving privacy.

This study finds that paternal exposure to ionizing radiation increases clustered de novo mutations in offspring, suggesting cDNMs as a transgenerational biomarker.

The paper evaluates a structured diagnostic framework for ultra-rare diseases, showing improved genetic diagnoses and novel gene-disease associations using exome sequencing and AI tools.