BioinformaticsExpert Systems with ApplicationsPeer-reviewed
Supervised contrastive learning enhances MHC-II peptide binding affinity prediction
Long-Chen Shen, Yan Liu, Zi Liu…·Dong‐Jun Yu
This paper introduces ConBoTNet, a deep learning model that improves MHC-II peptide binding affinity prediction using supervised contrastive learning and bottleneck transformers, achieving better performance than existing methods.