Author

Xingche Guo

University of ConnecticutORCID 0000-0003-2001-9879Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Dong CheniD· 1 shared Dongyuan SongiD· 1 shared Menghan LiiD· 1 shared Xu SuiD· 1 shared Xutao WangiD· 1 shared Yuxin YiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Dong ChenORCID

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1 paper

Recent·Most cited

Trustworthy super-resolution reconstruction across spatial omics modalities

Menghan Li, Xutao Wang, Xu Su, Yuxin Yin, Dong Chen, Xingche Guo, Dongyuan Song

This paper introduces spEnhance, a computational framework that improves spatial resolution and reliability of spot-level spatial omics data across multiple modalities.

bioRxiv · Sep 28, 2026 · PreprintBioinformatics