Author

Jai Santosh Polepalli

National University of SingaporeORCID 0000-0003-2004-2163Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Kevin JayarajiD· 1 shared Ritesh N. KumariD· 1 shared Shaikali Thameem DheeniD· 1 shared Sukanya ShyamasundariD· 1 shared Thiruma Valavan ArumugamiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperNeuroscience

Kevin JayarajORCID

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1 paper

Recent·Most cited

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

Kevin Jayaraj, Ritesh N. Kumar, Sukanya Shyamasundar, Thiruma Valavan Arumugam, Jai Santosh Polepalli, Shaikali Thameem Dheen

This study shows HDAC inhibition changes microglial activity and spatial distribution in stroke brains, promoting neuroprotection and recovery in mice.

Glia · May 26, 2025Peer-reviewedNeuroscience