Author

Brett Higgins

University of South FloridaORCID 0000-0003-2006-6704Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Ci Koehring· 1 shared Faiza Amber SiddiquiiD· 1 shared Forouzandeh FarsaeiiD· 1 shared Jiajia YangiD· 1 shared Kami KimiD· 1 shared Thomas KelleriD· 1 shared Thomas V. McDonaldiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Ci Koehring

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintJul 29, 2026

A highly penetrant LMNA R541C variant associated with dilated cardiomyopathy leads to dysregulation in metabolism and proliferation pathways in stem cell-derived cardiomyocytes

Thomas Keller, Ci Koehring, Brett Higgins…·Thomas V. McDonald

This study identifies a LMNA R541C variant linked to dilated cardiomyopathy and shows it disrupts metabolism and proliferation pathways in stem cell-derived cardiomyocytes.

DOI 10.64898/2026.07.20.739542

humanbulk RNA-seq

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