Author

Robert Siddaway

Hospital for Sick ChildrenORCID 0000-0003-2013-9467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Arun K RamaniiD· 2 shared Cynthia E HawkinsiD· 2 shared Mia HusićiD· 2 shared Michael BrudnoiD· 2 shared Michael J. ApostolidesiD· 2 shared Yue JiangiD· 2 shared Andrei L. TurinskyiD· 1 shared Man YuiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 34 mutual co-author links

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2 shared papersBioinformatics

Arun K RamaniORCID

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2 papers

Recent·Most cited

BioinformaticsBioinformaticsPeer-reviewedApr 19, 2021

MetaFusion: A high-confidence metacaller for filtering and prioritizing RNA-seq gene fusion candidates.

Michael J. Apostolides, Yue Jiang, Mia Husić…·Arun K Ramani

MetaFusion improves fusion detection by combining multiple callers, achieving higher precision and recall through standardized annotation and graph clustering.

17 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintOct 30, 2019

Found in Transcription: Gene fusions arise through defects in RNA processing in the absence of chromosomal rearrangements.

Yue Jiang, Michael J. Apostolides, Mia Husić…·Michael Brudno

The paper identifies RNA-specific gene fusions in tumors and normal tissues, showing they are linked to spliceosomal gene dysregulation and may contribute to cancer development.

DOI 10.1101/825570

humanbulk RNA-seq

𝕏 PostBluesky