Nico Papinutto

Paired CSF and blood scRNA/TCR-seq in treatment-naive MS shows a small set of expanded, cytotoxic CSF-enriched CD8+ clonotypes, two of which recognize EBV epitopes.

This study shows body size parameters significantly correlate with brain and spinal cord MRI metrics and should be included in neuroimaging studies.

This paper develops a method to reduce technical variation in multisite MRI data by aligning intensity distributions across scanners.

The paper introduces a statistical technique to count distinct multiple sclerosis lesions from MRI data, showing it correlates with gold-standard counts and provides disease-related insights.