Author
Division of Cancer Epidemiology and GeneticsORCID 0000-0003-2188-4223Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
G J M Shanika R Jayasinghe, Jianxin Shi, Rohit Thakur…·Nhan Do
This paper identifies 116 risk loci for melanoma through GWAS, links susceptibility to immunity and Wnt signaling, and develops a PRS improving risk prediction.
Jason W. Hoskins, Trevor A. Christensen, Daina Eiser…·Laufey Thora Amundadottir
This study identifies rs9581943 as a causal variant in a PDAC GWAS signal, showing it reduces PDX1 expression and impairs stress buffering in exocrine pancreatic cells.
Aidan O’Brien, Hyunkyung Kong, Harsh Patel…·Laufey Thora Amundadottir
The paper identifies functional variants and VNTRs at the 5p15.33 locus using fine-mapping, MPRA, and CRISPRi screens, revealing their role in cancer susceptibility through antagonistic pleiotropy.
Katelyn E. Connelly, Katherine Hullin, Ehssan Abdolalizadeh…·Laufey Thora Amundadottir
The paper fine-maps a PDAC GWAS signal at chr1p36.33 and identifies KLHL17 as a target gene regulated by JunB/D, with potential implications for inflammation and PDAC risk.