Aykut Erbaş

Multivalent lamin binding controls the meshwork structure in a self-assembled model of the nuclear lamina

This study uses a polymer-physics model to show how lamin binding parameters control nuclear lamina structure and mechanopathology.

Nonspecific steric hindrance of protein particles by lamina-associated domains

The paper investigates how lamina-associated domains (LADs) act as size-selective steric barriers to limit protein access to the nuclear periphery, providing a biophysical mechanism for gene regulation.

Peripheral heterochromatin tethering is required for chromatin-based nuclear mechanical response

The paper investigates how peripheral heterochromatin tethering influences nuclear mechanical response through simulations and experiments.

Phase Behavior and Dissociation Kinetics of Lamins in a Polymer Model of Progeria

This study models lamin aggregation and dissociation in progeria using polymer chains to show how molecular interactions and concentration affect nuclear lamina structure and stability.