Spatial multi-omics of multiple myeloma uncovers niche-dependent pro-myeloma and immunosuppressive signaling in the bone marrow and extramedullary lesions
Denis J. Ohlstrom, Marina E. Michaud, Mojtaba Bakhtiari…·Manoj Bhasin
This study uses spatial and single-cell transcriptomics to identify niche-specific signaling programs in multiple myeloma that drive progression and immunosuppression.