BiochemistryNature CommunicationsPeer-reviewed
Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase
Erin Skeens, Federica Maschietto, Ramu Manjula…·George P. Lisi
This study investigates the allosteric regulation of MKP5 by identifying the role of residue Y435 in maintaining the structural integrity of the allosteric pocket and its interaction with p38 MAPK and JNK.