BioinformaticsNature Computational SciencePeer-reviewed
Population-level comparisons of gene regulatory networks modeled on high-throughput single-cell transcriptomics data.
Daniel Osorio, Anna Capasso, S. Gail Eckhardt…·Marieke L. Kuijjer
This paper introduces SCORPION, a tool for reconstructing gene regulatory networks from single-cell RNA-seq data, showing it outperforms existing methods and detects consistent regulatory differences in colorectal cancer.