Systems BiologyCPT Pharmacometrics & Systems PharmacologyPeer-reviewed
Mechanisms of a sustained anti-inflammatory drug response in alveolar macrophages unraveled with mathematical modeling
Elin Nyman, Maria Lindh, William Lövfors…·Gunnar Cedersund
The paper uses mathematical modeling to uncover the mechanism of a sustained anti-inflammatory response to Dexamethasone in alveolar macrophages, identifying slow receptor-drug complex release as the key factor.
5 citations