BioinformaticsbioRxivPreprint
Unified somatic calling and machine learning-based classification enhance the discovery of clonal hematopoiesis of indeterminate potential
Shulan Tian, Garrett Jenkinson, Alejandro Ferrer…·Eric W. Klee
UNISOM improves CHIP detection from low-coverage sequencing data by combining variant calling with machine learning classification, identifying low-VAF mutations with high sensitivity.
DOI 10.1101/2024.04.22.590586