Author

Anirudh Chandra

Bhabha Atomic Research Centre, Mumbai;ORCID 0000-0003-2570-6790Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Biswajit SadhuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintNov 3, 2026

Long-range allosteric restraint by the Spiral-Pincer scaffold gates oxidative activation of the ATM kinase

Anirudh Chandra, Biswajit Sadhu

The paper investigates how the Spiral-Pincer scaffold regulates ATM kinase activation by oxidative stress, showing it restricts access to an oxidation-competent conformation.

DOI 10.64898/2026.11.02.763569

humanstructural biology

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