Coordinate control of the RNA polymerase II transcription cycle by CDK9-dependent, tripartite phosphorylation of SPT5
This study identifies tripartite phosphorylation of SPT5 by CDK9 as essential for regulating RNAPII transcription cycle phases, including pause release, elongation speed, and RNA processing.
bioRxiv · Jul 25, 2024 · PreprintMolecular Biology