Author

Pamela R. Kearns

Cancer Research UK Clinical Trials UnitORCID 0000-0003-2756-5813Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alastair SmithiD· 1 shared Alexander Winton· 1 shared Alexandra Curran· 1 shared Anindita RoyiD· 1 shared Aya Gouma· 1 shared Brenda E. S. Gibson· 1 shared Christine J. HarrisoniD· 1 shared David L.P. VetrieiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alastair SmithORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintApr 27, 2026

CD180 identifies chemoresistant stem-like blasts and reveals a KMT2A-driven vulnerability in acute myeloid leukaemia

Madonna M. Eltoukhy, Alexander Winton, Francesca Fasanella Masci…·Karen Keeshan

This paper identifies CD180 as a marker for chemoresistant stem-like blasts in KMT2A-rearranged paediatric AML, showing its absence on normal HSCs and its role as a therapeutic target.

DOI 10.64898/2026.04.23.720316

humanscRNA-seq

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