Author

Jean Laplanche

Assistance Publique – Hôpitaux de ParisORCID 0000-0003-2836-2903Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:GWAS summary statistics· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Christiane StehmanniD· 2 shared Inga ZerriD· 2 shared Jean‐Philippe Brandel· 2 shared Jiri SafariD· 2 shared Michael D. GeschwindiD· 2 shared Miguel CaleroiD· 2 shared Péter HermanniD· 2 shared Piero ParchiiD· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Christiane StehmannORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinePLoS ONEPeer-reviewedJul 26, 2024

Genome wide association study of clinical duration and age at onset of sporadic CJD

Holger Hummerich, Helen E. Speedy, Tracy Campbell…·Simon Mead

This study identifies genetic variants associated with clinical duration in sporadic CJD but finds no significant SNPs for age at onset.

8 citations

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsbioRxivPreprintSep 25, 2019

Gene-Gene interactions and pleiotropy in the brain nicotinic pathway associated with the heaviness and precocity of tobacco smoking among outpatients with multiple substance use disorders

Romain Icick, Morgane Besson, El‐Hadi Zerdazi…·Florence Vorspan

DOI 10.1101/782565

humanGWAS summary statistics

𝕏 PostBluesky

NeuroscienceNeurologyPeer-reviewedJun 6, 2019

Age of onset in genetic prion disease and the design of preventive clinical trials

Eric Vallabh Minikel, Sonia M. Vallabh, Margaret C. Orseth…·Simon Mead

This paper quantifies the challenges of designing preventive clinical trials for genetic prion disease due to high variability in age of onset, suggesting the need for biomarker-based trials.

104 citationstop 3%

humanstatistical model

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