Author

Christina K. Yung

Ontario Institute for Cancer ResearchORCID 0000-0003-2958-150XUnclaimed ORCID profile · follow to get notified of new preprints

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Christina K. Yung1 paper

Biology Disciplines

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Organism:human· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

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André KahlesiD· 3 shared Angela Norie BrooksiD· 3 shared B. F. Francis OuelletteiD· 3 shared Jan O. KorbeliD· 3 shared Junjun ZhangiD· 3 shared Marc D. PerryiD· 3 shared Nuno A. FonsecaiD· 3 shared Alvis BrāzmaiD· 2 shared

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2017-2020 · peak 1/yr

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3 shared papersGenomics

André KahlesORCID

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3 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedFeb 5, 2020

Whole genome and RNA sequencing of 1,220 cancers reveals hundreds of genes deregulated by rearrangement of cis-regulatory elements

Yiqun Zhang, Fengju Chen, Nuno A. Fonseca…·Paul Alan Edwards

The paper identifies hundreds of genes deregulated by SVs in cancer, showing increased expression linked to SV breakpoints and enhancer elements.

77 citationstop 2%

humanwhole-genome sequencing

𝕏 PostBluesky

GenomicsbioRxivPreprintMar 12, 2018

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types

PCAWG Transcriptome Core Group, Claudia Calabrese, Natalie R. Davidson…·Zemin Zhang

The paper analyzes RNA alterations across 27 cancer types using whole-genome sequencing data, identifying gene expression associations with DNA variants and structural fusions.

22 citations

humanwhole-genome sequencing

𝕏 PostBluesky

GenomicsbioRxivPreprintJul 10, 2017

Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

Christina K. Yung, Brian D. O’Connor, Sergei Yakneen…·Charles L. Short

The paper describes the PCAWG project's large-scale analysis of cancer whole genomes across multiple computing environments, producing validated consensus variants for downstream research.

28 citations

humanwhole-genome sequencing

𝕏 PostBluesky