Cell BiologybioRxivPreprint
A reversible GNAS-PKA-RUNX2 checkpoint governs skeletal stem cell fate in fibrous dysplasia
Sofía Cárdenas, Diego Rodriguez, Angelyn Solis…·Jorge Silvio Gutkind
This study identifies a reversible GNAS-PKA-RUNX2 checkpoint that governs skeletal stem cell fate in fibrous dysplasia and shows PKA inhibition can reverse disease features.
DOI 10.64898/2026.10.02.756293