Andrew Melfi

The paper analyzes the Wright-Fisher site frequency spectrum and shows how it differs from the coalescent approximation, particularly in singleton probabilities and frequency spectrum shape.

The paper develops a coalescent algorithm to calculate the site frequency spectrum (SFS) under varying mutation rates and population sizes, showing how mutation rate changes affect the SFS.

This paper investigates the validity of the Kingman coalescent approximation for large samples, showing when it holds and when triple collisions become significant.