Author

Joseph John Maleszewski

Mayo ClinicORCID 0000-0003-3239-6460Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Cristobal G. dos RemediosiD· 2 shared David J. TesteriD· 2 shared Evelyn T. Kim· 2 shared Johan Martijn BosiD· 2 shared John R. GiudicessiiD· 2 shared Joseph A. DearaniiD· 2 shared Michael John AckermaniD· 2 shared Ramin GarmanyiD· 2 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Cristobal G. dos RemediosORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular BiologyJournal of the American Heart AssociationPeer-reviewedOct 9, 2025

Mineralocorticoid Receptor Antagonism Reduces Atrial Arrhythmias Post-Cardiac Surgery and Attenuates Atrial Stress Responses to Cardioplegic Arrest

Sina Danesh, Fazal Wahab Khan, Trevor C. Chopko…·Paul C. Y. Tang

This study shows preoperative MRA use reduces new-onset POAF and long-standing AF development, with canrenone suppressing MR target genes linked to chronic AF in atrial cardiomyocytes during cold preservation.

7 citationstop 4%

humanbulk RNA-seq

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BioinformaticsJournal of Molecular and Cellular CardiologyPeer-reviewedSep 8, 2024

A Multi-Omics Atlas of Sex-Specific Differences in Obstructive Hypertrophic Cardiomyopathy

Ramin Garmany, Surendra Dasari, Johan Martijn Bos…·Michael John Ackerman

This study identifies sex-specific differences in multi-omics profiles of obstructive hypertrophic cardiomyopathy patients compared to controls.

11 citations

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintMay 9, 2024

Histone Modifications and miRNA Perturbations Contribute to Transcriptional Dysregulation of Hypertrophy in Obstructive Hypertrophic Cardiomyopathy

Ramin Garmany, Surendra Dasari, Johan Martijn Bos…·Michael John Ackerman

The paper identifies miRNA and histone modifications as contributors to transcriptional downregulation of hypertrophy pathways in obstructive hypertrophic cardiomyopathy.

1 citation

humanChIP-seq

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GeneticsEuropean Heart JournalPeer-reviewedJul 20, 2018

A Comprehensive Evaluation of the Genetic Architecture of Sudden Cardiac Arrest

Foram N. Ashar, Rebecca N. Mitchell, Christine M. Albert…·Nona Sotoodehnia

This study evaluates the genetic architecture of sudden cardiac arrest through GWAS and Mendelian randomization, finding genetic correlations with CAD, height, BMI, and electrical instability traits.

86 citations

humanGWAS summary statistics

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