Single-molecule analysis sheds light on cardiac myosin dysfunction due to hypertrophic cardiomyopathy mutation A57D in ventricular myosin light chain-1 (MLC1v)
Tianbang Wang, Emrulla Spahiu, Tim Holler…·Mamta Amrute‐Nayak
This study investigates the molecular mechanism of cardiac myosin dysfunction caused by the A57D mutation in MLC1v using single-molecule analysis and computational modeling.