BiochemistryChemistry - A European JournalPeer-reviewed
The ability of enzymes to preserve reactive conformations with well-positioned residues during enzyme-catalyzed reactions can be an important factor for efficient catalysis: a case study of CARNMT1
Mingling Yang, Hao Deng, Adua Rahman…·Hong Guo
This study uses computational simulations to show that preserving reactive conformations with well-positioned residues is critical for catalytic efficiency in CARNMT1, as demonstrated by comparing wild-type and mutant enzymes.
3 citations