Molecular BiologyPLoS ONEPeer-reviewed
Role of microRNA-21 in hypertrophic cardiac remodeling
Ken Watanabe, Taro Narumi, Tetsu Watanabe…·Masafumi Watanabe
This study investigates the role of miR-21 in hypertrophic cardiac remodeling, showing that its suppression prevents remodeling by regulating PDCD4, AP-1, and TGF-β1 signaling.