Lakshmi Rajagopal

Maternal influenza A virus infection in pregnant pigtail macaques dysregulates placental and fetal immunity, with disease severity correlating strongly with fetal, but not placental, immune perturbations.

This study characterizes three infection outcomes at the maternal-fetal interface in a nonhuman primate model and identifies gene expression patterns associated with infection progression, resolution, and inflammation.

The paper constructs a single-cell RNA-Seq atlas of the periventricular proliferative zone in late-gestation pigtail macaque fetal brain, revealing cell states similar to human fetal brain.

This study creates a single-cell RNA-Seq atlas of the pigtail macaque placenta in late gestation, revealing similarities to human placental cell populations.