Anthony D. Kappell

SeqScreen-Nano rapidly characterizes novel pathogens using ONT sequencing in resource-limited settings by identifying ORFs and classifying them functionally and taxonomically.

SeqScreen uses ensemble learning to accurately label pathogenic sequences with functional annotations, achieving high recall and precision for microbial pathogenesis.

This study evaluates NGS-based methods for detecting healthcare-acquired pathogens in simulated skin transmission events using metagenomic and metatranscriptomic sequencing.