Expression of short hairpin RNAs using the compact architecture of retroviral microRNA genes
James M. Burke, Rodney P. Kincaid, Francesca M. Aloisio, Nicole L. Welch, Christopher S. Sullivan
The paper develops a compact shRNA expression system using retroviral miRNA gene architecture, reducing coding space needed for shRNA expression by over two-fold compared to U6/H1 promoters.
Nucleic Acids Research · Jul 20, 2017Peer-reviewedMolecular Biology