Author

Colleen O’Ryan

University of Cape TownORCID 0000-0003-3719-4657Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Caitlyn MahonyiD· 2 shared Erin BuchananiD· 2 shared Sophia BamiD· 2 shared Emma FrickeliD· 1 shared Mignon van der WattiD· 1 shared Renaud Gaujoux· 1 shared Sofia Stathopoulos· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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2 shared papersMolecular Biology

Caitlyn MahonyORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 11, 2022

Molecular autism research in Africa: a scoping review comparing publication outputs to Brazil, India, the UK, and the USA.

Emma Frickel, Sophia Bam, Erin Buchanan…·Colleen O’Ryan

This paper compares molecular autism research publications from Africa, focusing on South Africa, with Brazil, India, the UK, and the USA, highlighting disparities in publication output and potential barriers.

DOI 10.1101/2022.11.11.516128

benchmark studybenchmarking

𝕏 PostBluesky

NeuroscienceFrontiers in Cell and Developmental BiologyPeer-reviewedJul 26, 2021

DNA methylation of PGC-1α is associated with elevated mtDNA copy number and altered urinary metabolites in Autism Spectrum Disorder

Sophia Bam, Erin Buchanan, Caitlyn Mahony, Colleen O’Ryan

The paper examines the association between PGC-1α DNA methylation, mtDNA copy number, and urinary metabolites in ASD, finding significant correlations in both ASD and control groups.

38 citations

humanDNA methylation

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GeneticsbioRxivPreprintApr 29, 2018

Genome-wide DNA methylation patterns in Autism Spectrum Disorder and mitochondrial function.

Sofia Stathopoulos, Renaud Gaujoux, Colleen O’Ryan

This study identifies differentially methylated loci in South African children with ASD, linking DNA methylation to mitochondrial metabolism and protein ubiquitination pathways.

5 citations

humanDNA methylation

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