Molecular BiologybioRxivPreprint
Human eosinophil cationic protein manifests alarmin activity through its basicity and ribonuclease activity
Ayush Attery, Irene Saha, Prafullakumar B. Tailor, Janendra K. Batra
This study shows that ECP, like EDN and HPR, has chemotactic activity for APCs and interacts with TLR-2 to activate NF-κB/AP-1, establishing ECP as an alarmin.