BiophysicsbioRxivPreprint
The Sec61/TRAP Translocon Scrambles Lipids
Matti Javanainen, Sudeep Karki, Dale Tranter…·Ville O. Paavilainen
The paper investigates the lipid scrambling activity of Sec61 and TRAP using molecular dynamics simulations, showing they facilitate lipid flip-flop via a credit card mechanism and are selective for phosphatidylcholine.
DOI 10.1101/2023.11.23.568215