GeneticsbioRxivPreprint
Enhanced genetic analysis of type 1 diabetes by selecting variants on both effect size and significance, and by integration with autoimmune thyroid disease
Daniel J. M. Crouch, Jamie R. J. Inshaw, Catherine C. Robertson…·John A. Todd
The paper identifies 302 new genetic signals for type 1 diabetes and autoimmune thyroid disease by combining effect size and significance, showing that only 28% of genome-wide significant signals have large effects.
17 citations