Harlan R. Barker

TFBSFootprinter predicts transcription factor binding sites across 124 vertebrate species using multiomic data, outperforming existing tools in accuracy.

The paper identifies regulatory differences between modern human and Neanderthal promoters, highlighting transcription factors and genes associated with brain development and neuropsychiatric disorders.

This paper uses bioinformatics to characterize ACE2 expression and regulation, finding higher expression in small intestine and specific cell types in trachea and lung.