Zoila Jurado

The paper introduces TMSE-BioCRNpyler, a library for mechanistic modeling of toehold-mediated strand exchange circuits, validated against existing models and supporting interoperability with standard formats.

The paper develops a chemical reaction network model for PURE cell-free expression systems to predict protein synthesis kinetics using mass-action reactions.

This study shows that MGapt fluorescence in commercial PURE systems is unstable and influenced by chemical factors like DTT, leading to inaccurate RNA measurements and proposes a model to predict these effects.

The paper builds and validates a chemical reaction network model for PURE protein synthesis using mass-action reactions, accurately predicting mRNA and protein production dynamics.