BioinformaticsFrontiers of Computer SciencePeer-reviewed
Flexibility and rigidity index for chromosome packing, flexibility and dynamics analysis
Jiajie Peng, Jinjin Yang, D. Vijay Anand…·Kelin Xia
The paper introduces a flexibility-rigidity index (FRI) model to quantify chromosome flexibility using Hi-C data, showing improved accuracy and efficiency compared to Gaussian network model (GNM).
4 citations