Author

Yongqi Liu

The Ohio State UniversityORCID 0000-0003-4209-6576Unclaimed ORCID profile · follow to get notified of new preprints

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Yongqi Liu2 papers · Peking University

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:Hi-C· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:simulation· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Shili LiniD· 2 shared Victor X. JiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersBioinformatics

Shili LinORCID

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2 papers

Recent·Most cited

BioinformaticsPLoS ONEPeer-reviewedSep 23, 2025

Can Random Walking on a Hi-C Contact Matrix Lead to Data Quality Improvement? An Assessment

Yongqi Liu, Shili Lin

This study evaluates random walk methods for improving Hi-C data quality, finding no significant benefit for TAD identification despite parameter tuning challenges.

1 citation

Hi-Cstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintJul 23, 2025

Novel Spatial-Structural-Zero-Aware Dissimilarity Measures for Subtype Discovery Using Single Cell Hi-C Data

Yongqi Liu, Victor X. Jin, Shili Lin

This study introduces szKendall, a dissimilarity measure for scHi-C data that accounts for structural zeros, improving cell clustering performance.

DOI 10.1101/2025.07.23.666407

Hi-Cstatistical model

𝕏 PostBluesky