Author

Xiaopan Chen

Zhejiang Provincial People's HospitalORCID 0000-0003-4289-7541Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Linjie CheniD· 3 shared Xiaobai HeiD· 3 shared Kundu Zhong· 2 shared Hong ZhangiD· 1 shared Hui HuiD· 1 shared Jiahao CaoiD· 1 shared Jianxin LyuiD· 1 shared Jinbang Shao· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Linjie ChenORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 24, 2026

Inflammatory suppression and cancer-associated bypass of the b0,+selenium-utilization program in the human intestine

Xiaobai He, Kundu Zhong, Yiyi Pu…·Linjie Chen

The paper identifies how inflammation and cancer alter the selenium-utilization program in the human intestine through changes in the b0,+ transporter and related redox pathways.

DOI 10.64898/2026.07.23.738870

humanscRNA-seq

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Molecular BiologybioRxivPreprintJun 24, 2026

The b0+ Amino Acid Transporter Defines a Selenium-utilization Enterocyte Program in the Human Intestine

Xiaobai He, Kundu Zhong, Wangzhen Yang…·Linjie Chen

The paper identifies the b0+ amino acid transporter system as a marker of a selenoprotein-enriched enterocyte state in the human intestine through single-cell transcriptomic analysis.

DOI 10.64898/2026.05.27.728150

humanscRNA-seq

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GeneticsbioRxivPreprintAug 29, 2025

Combining Selenocystine Based Fluorescence Assay with Structural Prediction for Enhanced Detection and Analysis of Cystine Stone Pathology

Xiaobai He, Xinyi Qian, Xiaoguang Zheng…·Linjie Chen

The paper develops a nonradioactive assay combining selenocystine fluorescence and AlphaFold for diagnosing cystinuria mutations and analyzing their functional impacts.

DOI 10.1101/2025.08.29.673186

humanproteomics

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