Steffi Gerlinde Riedel-Heller

This study performs APOE-stratified GWAS to uncover genetic mechanisms underlying Alzheimer's disease risk and response to therapies.

The paper develops and validates an LC-MS/MS method to quantify free queuine and queuosine in human plasma, finding no detectable Q but significant q levels with no gender difference.

The paper identifies high-priority missense variants in SORL1 associated with increased Alzheimer's Disease risk and earlier onset, suggesting clinical counseling considerations for carriers.

The paper investigates age-related changes in EEG biomarkers and their association with cognitive performance in older adults.

The paper identifies rare damaging variants in ATP8B4 and ABCA1 as novel risk factors for Alzheimer's Disease using exome sequencing data from 32,558 individuals.

The paper examines the relationship between animal-based product intake, weight status, depressive symptoms, and personality traits in a general population cohort.

This study examines the relationship between food addiction, obesity, and brain structure in a population-based sample, finding no significant neuroanatomical correlates of food addiction but some associations with BMI and orbitofrontal cortex thickness.

Genetic correlations across 25 brain disorders (215,683 cases) reveal broad psychiatric common-variant sharing, largely distinct neurological disorders, and migraine as the only significant cross-category link.

This study predicts brain-age from multimodal imaging data and finds it captures cognitive impairment with robustness to motion and generalizability across datasets.