Angela Andaleon

The paper conducts GWAS and transcriptome-wide association studies in Hispanic cohorts to identify genetic regulators of lipid traits, finding significant gene-tissue-phenotype associations that replicate in other populations.

The paper identifies trans-acting genes associated with complex traits by correlating cis-predicted gene expression with observed expression across tissues.

The paper investigates genetic architecture of gene expression across diverse populations, finding that predictive performance varies due to allele frequency differences and highlighting the need for diverse population sampling.