Author

John Tollen Fassett

University of GrazORCID 0000-0003-4591-6875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Bernd MayeriD· 1 shared Erin K. Fassett· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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1 shared paperPharmacology & Toxicology

Bernd MayerORCID

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1 paper

Recent·Most cited

AICAr inhibition of cardiomyocyte autophagy promotes p62-dependent NRF2 expression and protection against doxorubicin toxicity

Erin K. Fassett, Bernd Mayer, John Tollen Fassett

This study shows that AICAr protects cardiomyocytes from doxorubicin toxicity by inhibiting autophagy, increasing p62, and enhancing NRF2 activity through ADK-dependent mechanisms.

Cellular and Molecular Life Sciences · Nov 13, 2025Peer-reviewedPharmacology & Toxicology