Parallel erosion of a testis-specific Na+/K+ ATPase in three mammalian lineages sheds light into the evolution of spermatozoa energetics
Raúl Valente, André M. Machado, Eva Pericuesta, Daniel García‐Párraga, Nadia Artilheiro Artilheiro, Filipe Alves, Isabel Sousa-Pinto, Bernardo Pinto, J Miguel Cordeiro, Raquel Ruivo, Alfonso Gutiérrez‐Adán, L. Filipe C. Castro
The paper investigates the evolution of sperm energetics in mammals by analyzing gene duplication and loss of Atp1a4, revealing its role in sodium-dependent glucose uptake and subsequent pseudogenization in three lineages.
Genome Biology and Evolution · Jan 17, 2026Peer-reviewedEvolutionary Biology