Author

Aivar Sootla

University of OxfordORCID 0000-0003-4666-4454Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Antonis PapachristodoulouiD· 2 shared George H. Wadhams· 2 shared Nicolas J. Delalez· 2 shared Arthur Norman· 1 shared Emmanouil AlexisiD· 1 shared Harrison SteeliD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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2 shared papersSynthetic Biology

Antonis PapachristodoulouORCID

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2 papers

Recent·Most cited

Dichotomous Feedback: A Signal Sequestration-based Feedback Mechanism for Biocontroller Design

Aivar Sootla, Nicolas J. Delalez, Emmanouil Alexis, Arthur Norman, Harrison Steel, George H. Wadhams, Antonis Papachristodoulou

This paper introduces a new feedback mechanism for synthetic biology, dichotomous feedback, which uses signal sequestration to improve robustness and reduce noise in biological systems.

Journal of The Royal Society Interface · Apr 1, 2022Peer-reviewedSynthetic Biology

Design of a Synthetic sRNA-based Feedback Filter Module

Nicolas J. Delalez, Aivar Sootla, George H. Wadhams, Antonis Papachristodoulou

The paper designs and tests a synthetic sRNA-based feedback filter module that reduces noise and tunes feedback strength through mathematical modeling and experimental validation.

bioRxiv · Dec 21, 2018 · PreprintSynthetic Biology