Genetic & Genomic MedicinemedRxivPreprint
Scaling genetic discovery for organ volumes using machine learning-assisted imputation and bias-corrected GWAS
Afreen Naz, Brandon J. Whitcher, Altayeb Ahmed…·Hanieh Yaghootkar
This paper uses machine learning to impute MRI-derived organ volumes and applies bias-corrected GWAS to identify genetic loci associated with these traits across 450,000 individuals.