Author

Harkness C. Kuck

Nationwide Children's HospitalORCID 0000-0003-4755-6869Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Benjamin KellyiD· 1 shared David M Gordon· 1 shared Grant LammiiD· 1 shared James FitchiD· 1 shared James LiiD· 1 shared Jeff GaitheriD· 1 shared Peter WhiteiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Benjamin KellyORCID

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1 paper

Recent·Most cited

GenomicsGigaSciencePeer-reviewedApr 1, 2021

Global Analysis of Human mRNA Folding Disruptions in Synonymous Variants Demonstrates Significant Population Constraint

Jeff Gaither, Grant Lammi, James Li…·Peter White

The paper analyzes mRNA folding disruptions caused by synonymous variants and finds population-level constraints, introducing a Structural Predictivity Index to assess pathogenic potential.

36 citations

humanbulk RNA-seq

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