Igor Y. Yakushev

This study links human brain functional connectivity to neurotransmitter systems using resting-state fMRI and MEG across multiple cohorts, showing consistent patterns and clinical relevance.

The paper uses energy metabolism to infer directed communication patterns in the human cortex, showing sensory systems drive higher-order networks and default mode networks act as receivers.

This study shows that lateral ventricle volume oscillations drive CSF flow and clearance, influenced by cortical blood-volume changes and physiological drivers.

The paper investigates the energetic costs of neuromodulator signaling in the human brain and finds that evolutionarily novel connections have higher energetic costs than sensory-motor pathways.

This paper develops a large animal model for demyelinating brain diseases using minipigs, demonstrating reversible and multimodally trackable lesions that mimic human pathology.

The paper describes MRI and PET protocols used in the DIAN study to investigate preclinical Alzheimer's disease and reports key imaging findings.