Xinxin Lin

The paper uses single-cell RNA-seq to study liver and gallbladder development from the embryonic endoderm, identifying key transcription factors and gene expression changes during differentiation.

EPIP predicts MHC-I epitope presentation by integrating mass spectrometry-derived motifs and tissue-specific RNA-seq data, outperforming existing methods in independent validation.

The paper introduces scCAT-seq, a method to simultaneously assay chromatin accessibility and transcriptome in single cells, and demonstrates its application in human pre-implantation embryos to reveal regulatory heterogeneity.