Author

Jenny Lester

Cedars-Sinai Medical CenterORCID 0000-0003-4914-3275Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Beth Y. KarlaniD· 4 shared Anna DeFazioiD· 2 shared Anna JakubowskaiD· 2 shared Catherine J. KennedyiD· 2 shared Chad Daniel HuffiD· 2 shared Francesmary ModugnoiD· 2 shared Holly Ruth HarrisiD· 2 shared Ian CampbelliD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Beth Y. KarlanORCID

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4 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMar 5, 2026

Genome-wide classification of tumor-derived reads from bulk long-read sequencing

Toby M. Baker, Nedas Matulionis, Cassidy L. Andrasz…·Paul T. Spellman

ROCIT classifies tumor or non-tumor origin of reads from bulk long-read sequencing with high accuracy, improving somatic variant calling in tumors.

1 citation

humanwhole-genome sequencing

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Genetic & Genomic MedicinemedRxivPreprintFeb 29, 2024

Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk

Daniel R. Barnes, Jonathan P. Tyrer, Joe Dennis…·Kirsten B. Moysich

This study identifies seven novel genetic loci associated with high-grade serous ovarian cancer risk using a large-scale GWAS and develops polygenic scores for improved risk prediction.

3 citations

humanGWAS summary statistics

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GenomicsbioRxivPreprintAug 25, 2020

DNA methylation landscapes of matched primary and recurrent high grade serous ovarian cancers are preserved throughout disease progression and chemoresistance.

Nicole Gull, Michelle R. Jones, Pei-Chen Peng…·Simon A. Gayther

This study shows that DNA methylation and gene expression patterns are preserved in recurrent high grade serous ovarian cancers, with BRCA1/2 carriers showing more shared methylation changes and improved survival.

2 citations

humanwhole-genome sequencing

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Genetic & Genomic MedicineJournal of Medical GeneticsPeer-reviewedJun 16, 2020

Population based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high grade serous ovarian cancer

Honglin Song, Ed Dicks, Jonathan P. Tyrer…·Paul D.P. Pharoah

53 citationstop 4%

humanwhole-exome sequencing

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