Author

Francesmary Modugno

University of PittsburghORCID 0000-0003-0637-1534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:genetic perturbation / CRISPR· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Adam G. ChatoffiD· 2 shared Aidan R. ColeiD· 2 shared Amandine AmalriciD· 2 shared Andrea Andress HuacachinoiD· 2 shared Anna DeFazioiD· 2 shared Anna JakubowskaiD· 2 shared Apoorva UbovejaiD· 2 shared Baixue YangiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Adam G. ChatoffORCID

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4 papers

Recent·Most cited

Cancer BiologyNature AgingPeer-reviewedJul 30, 2026

The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming

Aidan R. Cole, Raquel Buj, Apoorva Uboveja…·Katherine M. Aird

This study shows that chemotherapy-induced senescence-associated secretome promotes metastasis in ovarian cancer by reprogramming metabolism and increasing cell detachment.

6 citationstop 3%

humanbulk RNA-seq

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Cancer BiologyNaturePeer-reviewedMay 27, 2026

αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

Apoorva Uboveja, Baixue Yang, Raquel Buj…·Katherine M. Aird

This study shows that αKG-mediated carnitine synthesis supports HR proficiency by promoting histone acetylation, which enhances DNA repair.

10 citations

humanproteomics

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Genetic & Genomic MedicinemedRxivPreprintFeb 29, 2024

Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk

Daniel R. Barnes, Jonathan P. Tyrer, Joe Dennis…·Kirsten B. Moysich

This study identifies seven novel genetic loci associated with high-grade serous ovarian cancer risk using a large-scale GWAS and develops polygenic scores for improved risk prediction.

3 citations

humanGWAS summary statistics

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Genetic & Genomic MedicineJournal of Medical GeneticsPeer-reviewedJun 16, 2020

Population based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high grade serous ovarian cancer

Honglin Song, Ed Dicks, Jonathan P. Tyrer…·Paul D.P. Pharoah

53 citationstop 4%

humanwhole-exome sequencing

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